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Diabetes is an illness, no sugar absorbed properly by the body. Two type 1 and type 2 diabetes is a central element: hyperglycemia (glucose) shortcomings by insulin, a hormone produced by the pancreas. Globally, the incidence of diabetes is expected that 250 million people beyond 2025 – including 35 million heart attacks, 13 million strokes, 6 million episodes of renal failure, 8 million cases of blindness or eye surgery, 2 million amputations and 62 million deaths – which is a measure of the magnitude of the problem. Although diabetes is high on the agenda of the health care industry, it has not yet received this position. According to the American Diabetes Association, there are 21 million diabetics in America, with another 54 million people with pre-diabetes (high risk of developing diabetes type II). This is equivalent to 75 million Americans suffering from diabetes or high risk. Most doctors believe that diabetes is curable … That is what they have learned. The best we could hope – for what they have learned in medical school – is to “control” the disease with medication and insulin. And they are right … Diabetes is incurable, if you delete the more doctors advice from your diabetes symptoms, only to follow the drug. Although prescriptive medications can help, “to control artificial” your sugar in the blood, they do nothing for the cause of the disease. As we all know that prescription drugs mask (diabetic) symptoms only. They do not heal, they actually worsen the problem because they weaken the immune system. That means to help you even worse. Unfortunately, drug use are 2 diabetics. Five times more often from heart disease than those who die by diet alone treatment. And yet, there are side effects of drugs. These include problems with the liver (jaundice), rash, anemia, and sometimes death. Both oral antidiabetic drugs and insulin are not health options tailored. They accelerate the appearance of aging and damage to liver, heart and other organs leading to further complications. But there is a solution. Diabetes is curable. It is not treating the symptoms with drugs that cure only to perpetuate the state. Please understand, these drugs are the biggest fraud in the history of mankind orchestrated. The solution is to find the cause of diabetes by stimulating the body to your pancreas to produce more insulin, and of course the new address without the complications or side effects of drugs and medications. Why do we hear this information from the American Diabetes Association? The truth is, the American Diabetes Association benefit greatly from the recent trend in diabetes. They will be sponsored by pharmaceutical companies would lose out if people reversed there diabetic conditions. The treatment of diabetes results in U.S. dollars over 10 million dollars for each hour of the day, to provide physicians, pharmaceutical companies, and testing. With so much money at stake Big Pharma in the extreme to go to silence information about natural remedies and alternatives for the treatment of diabetes. But the truth is that the reverse diabetes is not only possible, it is likely if you’re willing to put in the effort and follow a few simple steps and proven. diabetes every day more and more to find they now have literally reverse the disease.

Diabetes is a serious disease. If nothing is done, it can have serious consequences, including death. Fortunately, there is a disease that can be managed. Unfortunately, most people with diabetes and not know they have and therefore should not be treated until it becomes very late. If you suspect you have diabetes, it is very important that you work quickly to attract attention and determine if you have it. Diabetes mellitus occurs when there is not enough insulin is produced or when the available insulin does not function properly. Without insulin, the amount of glucose in the blood is abnormally high, which causes the unquenchable thirst and frequent urination. The body of the inability to use or store glucose causes of hunger and weight loss. The tissues and cells, from which human bodies are living things need food to stay alive. The cells eat food is a type of sugar called glucose. Fixed, as are the cells of the body depends entirely on the blood in which they bathed, having to make glucose. Without access to adequate glucose, the body’s cells do not benefit of fuel (a process known as metabolism) and soon die. Diabetes occurs because some people do not or can not meet his insulin, a hormone naturally. Please help us, hormones control the functioning of our bodies. Insulin, the specific task is to regulate the body use glucose, our main source of energy. We get glucose, a form of sugar, from which we eat. It is also formed by the liver What Causes Diabetes Diabetes (actual name is diabetes mellitus) of any kind is a disease that prevents the body to use food properly. Normally you will have the main source of energy in the body from glucose, a simple sugar from foods rich in simple carbohydrates (such as table sugar or other sweeteners such as honey, molasses, jams and jellies, beverages drinks and cookies), or degradation of complex carbohydrates such as starch (bread, potatoes and pasta). The damage caused by diabetes can best be reduced by preventing the onset of type 2 diabetes. Prevention of modifying risk factors – particularly by changes in lifestyle – is an objective of the National Diabetes Strategy (CDHA, 1999), which was approved in 1999 by all States and Ministers Commonwealth Health. This goal was also in the National Framework for Service Improvement in diabetes stresses (NHPAC, 2006a). Risk factors for diabetes Age: All people are vulnerable to the disease in their lifetime. However, the risk is higher, as you age. It is a gradual increase in sensitivity, with hint at puberty and during pregnancy, reaching the age of 40 years. Then there is a quick jump. There are different types of diabetes. Gestational diabetes begins during pregnancy and disappears after childbirth. Another type is as juvenile diabetes (known in children) or Type I (young adults). These individuals usually develop their disease before the 20 year life. People with type I diabetes must take insulin injections every day. About 10 percent of all people with type I diabetes (also called insulin-dependent). Type 2 diabetes in this way, some insulin your pancreas, but not enough. Your cells also can become resistant to the effects of insulin, insulin to be sufficient to maintain the monitoring of glucose in the cells of your body. Type 2 diabetes usually develops after the 40th year of life.

Type 2 diabetes is the most common form of diabetes. Although it is a chronic disease that can lead to other serious diseases, and sometimes fatal diseases, there are treatments for type 2 diabetes, the successful work in the prevention and treatment of disease. Type 2 diabetes treatment The treatment of type 2 diabetes requires a lifetime commitment. The aim of the treatment plan for type 2 diabetes control levels of blood sugar in the body and help your body’s cells less resistant to insulin. When you have diabetes type 2, or even if you are diagnosed with a higher risk of developing the disease, it is important that type 2 diabetes treatment and prevention plan begins as soon as possible. Successful treatment of type 2 diabetes plan is to monitor your blood sugar in the blood, and things that minimize the appearance of symptoms included. If you have been diagnosed with type 2 diabetes, the first step in your treatment plan for type 2 diabetes is to learn and learn as much as possible on prevention and treatment of disease. The disease is a chronic disease in life that can lead to the emergence of more serious and sometimes fatal diseases like heart disease and stroke. There are certain things that can cause changes in your blood sugar in the blood. That includes food, lack of physical activity, medications, diseases, alcohol, stress and experience of fluctuating hormone levels of women during the menstrual cycle. can identify factors that contribute to changes in your blood sugar in the blood and monitor your blood sugar regularly can help reduce the risk of high levels of sugar in the blood. A very important program for type 2 diabetes is a healthy diet. There are many foods that contribute to increased blood sugar, and although it is not necessary to completely avoid these foods, it is necessary, those foods with a healthy diet for the remaining high in the low fat diet. A healthy diet should include plenty of fruits and vegetables, whole grain foods. Not only a healthy diet will give you more energy and feeling generally good, but a healthy diet with regular exercise together can help eliminate obesity, one of the leading factors in the development Type 2 diabetes. Regular exercise can help a healthy diet to prevent or delay the onset of symptoms of type 2 diabetes. Regular exercise helps your muscles, cardiovascular system and nervous system – all pulling together to make your cells less resistant to the insulin your body produces naturally. For some people, a treatment for type 2 diabetes, which includes a healthy diet, regular exercise and adequate monitoring of blood glucose levels close enough to cause illness and a deterioration in early to avoid more serious complications. In those cases, your doctor may recommend include type 2 diabetes drugs or insulin treatment plan. Before you cover treatment, medication, start with your doctor about possible side effects and interactions with other drugs or foods that may arise for discussion. lifelong commitment Successful treatment of type 2 diabetes plan requires a lifetime commitment to a healthy lifestyle includes leaders to prevent blood glucose monitoring and working conditions or delay the serious complications that may be caused by diabetes Type 2. As with most anything you throw in life is education going to get the key to your success. And in the case of type 2 diabetes, the adage “prevention is better than cure” is located locally. Type 2 diabetes is a disease that leads to a healthy lifestyle as soon as possible in life can be avoided. No only reduce the risk of contracting type 2 diabetes, but decreases the risk of many other diseases that can be very serious and deadly. Remember, healthy is healthy.

There is no other type of diabetes are many types of diabetes, but the three most common are: Type 1 Type 1 second-2-3. These three types of gestational diabetes are the same with minor differences, all people with diabetes has one thing in common, and that little or no ability to move glucose from blood into cells where it is converted in the body fuels primary. We all have glucose in the blood, if we do not have diabetes. Main source of glucose is the food we eat. When we eat, the digestive system breaks food into glucose, which is absorbed into the blood in the small intestine. People with diabetes are not dependent on insulin, a hormone produced by the pancreas to move glucose from the blood into the body of billions of cells. But people who have diabetes either do not produce insulin or can not effectively use the insulin produced in the body. Without insulin, glucose, blood cells Moving AOT. Scientists do not cause the exact reason behind SOA diabetes, but it seems to be the result of a combination of genetic and environmental factors, including viral infections, poor diet and lack of exercise. So far, no solution has diabetes, but the good news is that the disease can be managed and treated. People with diabetes can live fulfilling, healthy life. Type 1 diabetes Type 1 diabetes, also called insulin-dependent diabetes or IDDM is not known to produce insulin and need regular care to keep insulin, blood glucose levels normal. Type 1 diabetes has been described as a diabetes of youth, but the name was changed because Type 1 diabetes affects young and the elderly. Risk Factors A family history of diabetes increases the risk for future generations. Diabetes can occur in any partnership, but it is more common among whites. Half of type 1 diabetes are under the age of 20 years. His 20 years of age or younger increases the risk. What are the causes? Most children whose parents are diabetic, do not suffer from the disease, but scientists still believe that heredity plays a major role in type 1 diabetes because it tends to run in families. Researchers have increased several genes, the risk of type 1 diabetes research appears. But they have not a single gene, which had caused diabetes. Type 1 diabetes has many characteristics of an autoimmune disease. In autoimmune diseases, the immune system, protects against disease by killing invading germs. In the case of type 1 diabetes, the immune system destroys the cells in the pancreas that produce insulin. Type 1 diabetes often occurs shortly after a viral infection, and doctors sometimes diagnosed announced a sharp increase in type 1 diabetes after viral epidemics. About 95% of patients with type 2 diabetes type 2, also called non-insulin-dependent diabetes or NIDDM. Type 2 diabetes produce insulin but cells resistant to insulin their bodies, “they can not adequately respond to the hormone, so glucose accumulated in the blood. Some people with type 2 diabetes insulin injections, but most of the disease by a combination of weight loss, exercise, control of oral prescription drugs against diabetes and strict control. Similar risk factors for type 1, type 2 disease also results in families and increase the risk for future generations. Most patients diagnosed with type 2 are above the 30-year or more. Half the new cases are between 55 years and older. In a comparison between whites and Asians, Type 2 diabetes is more common in Native Americans, African Americans, Latinos found, and Hispanics. Insulin resistance leads to increased weight and reduced physical activity.

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To compare the role of drug glibenclamide and pioglitazone in type 11 non-insulin-dependent diabetic patients. Authors: Raj Kumar Chohan, Ghulam Rasool Mashori, Ghulam Rasool Bhurgri, Shamim-u-Rehman Mustafa DahriGhulam, anise-u-Rehman. Introduction: Diabetes is the Greek word for “siphon” What is the first member and means for much of the urine is made. TRM “sweet” comes from a word Laton “filled” Honey “and was used by, because the urine was sweet (Wheeler, 2004) ketaocidosis diabetes is a life-threatening condition that some of hospitalization and treatment data. Recognition of this condition is almost important as even small delays can have an impact on survival (Nattrass 2006). Hypoglycemia induced by insulin in episodes in diabetic patients. Probably the most important factor for the prescription of insulin-treated patients achieving the goals necessary to prevent complications of diabetes, glucose. The incidence of hypoglycemia reflects the current inadequancy Mathod of insulin delievery cause inappropriate insulin OT concentration high, especially after eating some food at night blindness, and even more important risk factor for heart disease and stroke (Heller, 2003). Diabetes type 1 diabetes MELLITUSTYPE (DID): Type I diabetes occurs in children of all ages, both sexes and all groups athenic. Type 1 diabetes usually occurs through mechanisms. It is most common metabolic condition in children and adolescents (Bui, 2004). Type1diabetes is the immunological destruction of pancreatic B cells characterized by insulin deficiency. This leads to a common biochemical endpoint of the risk of hyperglycemia and ketoacidosis, but clinical Presentaion varies depending on the speed and degree of failure of B cells (Lambert & Bingley. 2005). Diabetes mellitus type II (NIDDM) Type II diabetes is a complex metabolic disorder associated with dysfunction of these B cells and with various degrees of insulin resistance major pathogenic factors of insulin resistance leads to diabetes type 2 and decreased insulin secretion, resulting from changes caused by the liver, skeletal muscle and pancreatic beta cells (Charles & Clark, 1996). Diabetes mellitus gestational diabetes mellitus: women who develop glucose intolerance, in late pregnancy and women with previously diagnosed diabetes. SECONDARY diabetes mellitus: Diabetes is a disease caused by secondary pancreatic system endocrime, genetic disease, or exposure to chemical agents. Type I diabetes – formerly called diabetes mellitus insluin (DID), the destruction of pancreatic beta cells that produced marked inslulinType – I-diabetes, formerly known as diabetes mellitus (IDDM), known characterized by destruction of cells beta in the pancreas, insulin is produced. Type 1 diabetes occurs most frequently in children and young adults, but it may be, at any age. (Anderson et al 2007). Type-11 diabetes is not only uprward. A pancreas that produce insulin insufficient. muscle cells of the liver, too much glucose, does not easily take in glucose release. (McCarren, 2008) Many genetic factors are involved in the development of diabetes. Because of the new genetic method to identify all the researchers closed the door cadidate gene for both non-insulin diabetes (Bernhard, 1995) dependent and insulin dependent. Women who had gestational diabetes are more likely to develop type 11diabetes itself. Women with diabetes are more disadvantaged group Pergnant. You need more intensive prenatal care and close monitoring of blood glucose, blood pressure and weight. (Jawed2006) Overweight children the progression of childhood obesity in adulthood should be developed with early complications, including diabetes and associated cardiovascular disease IgpG2. diabetes is the most common clinical form of diabetes accountingforabout 1990% of all cases, it is currently the global epidemic. 11diabetes mellitus by the use of infectious endogenous insulin is due, it is often the result of obesity and physical inactivity (WHO, 2007). PREVALACES & IINCIDENCE: Diabetes mellitus increases with age, 200 of the prevalence of diabetes was estimated at 0. 19% Persons <20 years and 8 6% in men> 20 years. It is considered the geographic variation in incidence of type 1 and type-11 in both diabetes mellitus. Scavandinvian has the highest incidence of type 1 diabetes in Finland, e. g, the incidence of 35/100, 000 € per year in the Pacific, at a price much lower in Japan and China the incidence is 1 to 3 / 100, 00 per year of type 1 diabetes, Europe North and from the United States a couplet (8to17/100, 000 per year). The prevalence of diabetes mellitus type 11 is the highest in Iceland some Pacific, intermediate in countries like India and the United States, and relatively low in Russia and China. This variability is probably due to genetic resources, environmental factors and beharioral (Power, 2005). Diabetes mellitus is also prevalence between different ethnic groups in a given country, it is usually directly applicable ethnic groups have their prevalence with age and increased more than 5% of people aged over 65, diabetes mellitus (David Owerback 1988). The global prevalence of diabetes has increased over the last two decades. The prevalence of diabetes mellitus type11 is expected to type 11 diabetes more frequently in Hispanic Native American, African, American, and Asians, Pacific Islanders, for non-Hispanic whites, the incidence is approximately equal Women and men in all population groups. Diabetes Type 11 is becoming more common as people live longer, and the prevalence of diabetes increases with age also seen more often than ever among young people, in conjunction with the rise of obesity Children prevalenceof type11 diabetes are still many countries with estimates, but in cases of diabetes in 2000and 2030th rank among people with diabetes Country2000 countries (milloin) Country2030 diabtes people (in millions) India31. 7India79. 47China20. 8China42. 3USA17. 7USA30. 3Indonesia8. 4Indonesia21. 3Japan6. 8Pakistan13. 9Pakistan5. 2Brazil11. 3Russian federation4. 6Bangladesh11. 1Brazil4. 6Japan8. 9Italy4. 3Philippines7. 8Bangladesh3. 2Egypt6. 7 (Wareham and FOROUHI 2oo6) drug treatment of diabetes mellitus: the biguanides lower blood sugar, they increase glucose uptake and use in skeletal muscle by reducing insulin resistance and reduce hepatic production of glucose (gluconeogenesis). lower blood sugar, like a bar MEASUREMENT reduced low and very low lipoprotein MEASURE (LDL and VLDL) and metformin has a half-life of approximately three hours and is excreted unchanged in urine. clinical type 2 diabetes who are overweight and are used to failure of treatment with metformin alone food. Adverse effects are dose-related gastrointestinal e. g anorexia, diarrhea, nausea, lactic acidosis produced rare but potentially fatal toxic effects. (Dale, 2003). Improved insulin sensitivity by activating certain genes involved in lipid synthesis and metabolism of carbohydrates and Rosigilitazone Piogiltazone are currently authorized. Thiazolidinediones. Thiazolidinediones do not cause hypoglycemia when used alone, but they are usually taken in combination with sulfonylureas. In some studies incouraging, thaiazolidiniones have very positive effects on the heart, including reducing blood pressure and enhancement products and triglyceride levels Cholestrol, including increased levels of HDL, the good Cholestrol. You can also block a molecule called 11 Best CSH which can play an important role in the metabolic syndrome and diabetes type11. A study that rosiglitazone may even improve the function of beta cells sugessted and thus prevent the progression of diabetes. Anemia, weight gain, increased risk of body fluid can worson heart failure. Troglitazone was, after some reports of heart failure. Liver failure withdrawn death Abd. Current Grant Thiazoldinediones not seem the same effects on the liver, although there are few reports of liver damage. In patients with failure dietry choice of a sulfonylurea or insulin therapy is controversial and empric benefit of insulin therapy are education, improving the postmark diagnosis reported receiving treatment for short-term intense untreated diabetes type 2 (Scarlett et al, 1984) sulfonylurea Two other groups or generations for their efficacy, duration, drug interactions, side effects profiles. Sulfonylureas enhance insulin action in cells placed in culture and stimulate the synthesis of glucose transporters (Jacobs et al 1998). A sulphonylurea drug should normally be the insulin secretagogue of choice, NICE (National Institute for Clinical Excellence) recommends that the generic drug must be perscribed (Scsade and al1998). RESEARCH Design and Methods: This study was in the deprtment Pharmacololgy and Therapeutics, Basic Medical Sciences Institute Jinnah Postgraduate Medical Centre, Karachi, under the supervision conducted DRR kind od: GhulamRsool Mashori, associate professor and head of the Department of Pharmacology and therapeutic colloboration with the medical department and a filter Unit111 clinic, medical service, JPMC, Karachi. Seventy NIDDM (Type II) diabetic patients were initially in the study of the Clinic Filter Type III at the Medical Unit and diabetic clinic. Of the 60 diabetic patients have been throughout the remaining period of the study involved 10 patients were discontinued due to poor comlpiance or change in residential areas instead. All patients were divided into two main groups, groupies and group II patients were selected in this study after the inclusion and exclusion. Inclusion criteria: patients newly diagnosed Diabtes non-insulin dependent mellitus. Diagnsed diabetes patients in their homes, have no history of any drug. Having both sexes aged between 30-60 years. patients with non insulin Depedent were treated with pioglitazone. patients diagnosed with non Imsulin Depedent mellitus, drug glibenclamide. CRIRERIA EXCLUSION: Patients with high blood pressure. Patients with liver disease. Patients with heart disease. Pregnancy and breastfeeding women. Patients with renal insufficiency. Patients with severe complications. MATERIAL laces. Lancet Hlder (TM2 many abbots Easy Touch ASEE 03). Glucometer (Medisense) optilim One Touch (Abbott). Blood Sugar trpis nest (for vitro diagnostic (IVD Labortries Abbott Medisense UK Ltd, Abigngdon, Ox14ITR, MASD UK). stored at least 30?, (4 ° -30 ° C) and a maximum 40 ° C (39 ° -86 ° F). Weight Machine Model 1101 Lot no. TANTIATA 312th. DRUGSTab: Daonil 5 mg (Aventis Pharma) class of drugs: a sulphonylurea. Generic Name: glyburide. MFGLIC: No 000 007 FB-No. 000220MFG date: 12:00 06EXP days :7-10Lot NO: B230Tab: Pioz (Hilton Pharm) PvtLTd. Tab: Poizer 15mgDrug Category: Thaiazolinedione. Generic Name: pioglitazone hydrochloride. MFG LIC: 000 W Registration No. 136 dated :3-03270MFG 06EXP Date: 3-o9Lot No: 6287Tab: Poizer (Hilton Pharma) Pvt Ltd PARAMETERS: fasting glucose (FBS). random blood sugar (RBS). weight. Tags Keywords: diabetes, diabetes non-insulin and diabetes-insulin depedent, Daonil, poizer from the insulin. RESULTS: Table 1Weight observed and blood glucose at baseline and day 0cm group11 group1 group 1Group pioglitazone, n = 11 n = 33Weight63 27Glibenclamide. 2 7 + 37 + 15 25 ° 56 ° 62nd Sugar172 fast. 7 + 13. 32 42 +12 188th o5 · Random blood Sugar285. 11 + 15 + 17 18 532 284th ° 07 °, all values mean ± SEM. Imagine a weight and blood glucose levels observed are expressed in early (Day-O) in Table No. shpwing body weight (bw) and blood sugar (msg/dl0 levels, observed at baseline (day 0) in both groups group11 9group: 1 &) Groups: 1 Weight (Kg’s) mean + SEM) 63 37 ± 2 Fasting blood glucose 25 ± 7 13 32 172nd, 285th and random blood sugar 11 ± 15 32 Group: 11 Weight (KG’s0 (mean + SEM) 62 7 ± 1 56 to fasting (42 ± mg/dl0 2005 12th 188th, 284th random blood sugar of 18 ± 03 17th Figure 2: List of weight and glucose levels observed reference (day 0) in group 1 and group 11 Weight: 9 kg), their average values 63rd 37.62. 7, fasting (mg / dl) is located at 172nd 71 188 42 Random blood glucose (mg / dl) 285 284th 18th 11 & TABLE: All parameters in the observation 2Peroidic Group1Goup1 (pioglitazone) n = 27 P-day 90Weight63 0 days 45days 90days-45-0to45Day. 37 ± 2 2563. 63 ± 2 63 ± 2 2663rd 23> 0 05 (NS)>; 0th 05 (NS), fasting blood glucose sugar172. 7 165 13 ± 32. 04 ± 98 153 8. 37 ± 7 59> 0. 05 (NS) 0 05 (NS), random blood sugar285. 11 ± 15 32 279. 63 255 78 ± 13. 56 ± 12 65> 0 05 (NS)> 0 05 (NS) All values are mean ± SEM shown. (NS) not significant. Table: 2Showing regular observations of all parameters in group 1 (piogiltazone) (No. 27) the weight value P (day 0 to day 45)> 0 05 (NS). FPG> 0 05 (NS) of random blood glucose> 0 05 (NS) P. Day 90 weight values> 0 05 (N. S), FBS> 0 05 (N. S) 7RBS> 0th 05 (N. S) SIGNIFICANTFIGURE NO: 2 showing the regular monitoring of all parameters in group 1 in 45 days and 26.63 days day0 90th-average weight (kg) 63 37.63 .. 63 FBS ( mg / dL) 172 7165. 04 153. 37, RBS (mg / dl) 285 11 279 78. 255 56. TABLE NO3Peroidic monitoring of all parameters Group11 Group 11 (glibenclamide) N = 33P-Day value 45days 90days 45days 0 days -0-of-45 90Weight62. 7 ± 1 64 ± 5665th 1064th second 55 ± 1 92> 0 05 (NS) 0 05 (sugar188 blood NS0Fasting. 42 ± 12 05 168 45. 99 140 ± 10. 06 ± 5 68> , 0 05 (NS)> 0 05 (S) random blood sugar284. 03 220 18 ± 17. 12 170 13 ± 39. 94 ± 5 80 <0005 (MS) 0002 (ms0 (a) significant (MS) values are mean ± SEM significantAll moderate. No3 expressed table: See the regular monitoring of all parameters in the Goupe: 11 groups: 11 with drug (glibenclamide) None of the patients (n = 33). It P-value is the day 0 to day 45> weight 0th 05 (NS), FBS> 0 05 (N. S) RBS <0005 (MS) <0th 01 – day and day 45-90 weight> 0 05 (NS) FBS (0 05) RBS <0002 (Mr. S0 moderately important. Figure 3: Shwing regular observations in all parameters of the 62nd Group 11 Weight 7.65. 64.64. 55 FBS (mg / dl) 188 42 168. 45 2006 140e RBS (mg / dl) 284 18 December 220th, 170 94 (day 0 days 45-90). Talk: In Denmark, Al Beck Nielsenet, Skillman TG (1981) of published studies show that building glibenclamide increased number of receptors on monocytes of patients with diabetes mellitus type 11. Some patients were treated with diet and were in the second generation agents sulfonyureas Cobin. The number insulin receptor, patients measured before and after treatment. Intrvenous glucose test shows insulin secretion afterthe sustained impairent starting point for drug therapy. However, patients who were drug pioglitazone some results in the secretion of insulin were obtained in violation of drug therapy early in development. Clinical observations have suggested that the second generation sulfonylureas can effect through a potentiation of insulin-stimulating insulin-secreting primary other drugs released into the year. After studying and treating WilliamC Dukworth al (1972), AFTRS, review with sulfonylureas is well documented that plasma insulin levels fell in response to oral glucose load. This place apparently has much glucose tolerance improved during treatment, the levels of this study clearly support that study. The result of the above is correlated with the research group 11 Bonnie & Kimmel (completed in 2005) produced the same results FBS reduced basis, and at the end of the study with a total reduction of 44% the 23th, while the results showed at the end of the study were p-value peroid (p <0.001 ). Alvarsson Even Michael et al (2003) the same type of study and found, and the general trend of the change in 22 years. 11% FBS and 40% resulted in 88 rbs at the end of the study was p-value (p <0001). But a study conducted by (Stone & Brown (2003) more didnot our results within the parameters of FBS and observers, a reduction of 26 years. 22%. CONCLUSION: In light of the discussion is that it is obiovus study, glibenclamide was more effective, consistent and safer than pioglitzone in a short time. Diabetes mellitus is a chronic disease to extend for a lifetime . poor communities can afford to go to the marketing of drugs to Pakistan for diabetic patients and easily buy purchase costs, in fact, most people do without perscription pharmacy RD because pharmacists to know and patients both on the disease. As dispirin as an analgesic, it is a drug known anti-diabetics in our country compared to other diabetes drugs. refernce: Anderson J, Kendall Perryman. S et al, “Diet and Diabetes” Diabetes 2006.16 (3) :17-19-Bui H type 1 diabetes in children medicine therapyin 2006.3 diabetes Diabetes Care Diabetes 0.1-11 3Bernhard 1995.19 (100:12-17-MC-Clark oral pharmacological type11 diabetes and clinical use of the existing use of the agent are currently available diabetes 1998.11 (4) :211-221. Carren M. Types of diabetes mellitus Diabetes 2006 10 (3) 0.07-David Owerback NJ-population prevalence of diabetes Diabetes 1988.02 (6) :31-32Dale MM, diabetes mellitus pharmacology 20035th edition :287-391st Heller SR – hypoglycemia and diabetic ketoacidosis hypoglycemia 2006:34 -Medicine (03) :102-110. Untraveling Jawad F of Mystry Diabetes’Diabetes 2006, 15 (3) :13-15. Jacobs, D, insulin for diabetes in 1998, 6 (3) 1160126. Bingliy Lambert the basic facts in medicine 2006.34 (6) :3-7. Natters M-and hyperglycemia-Ketoacdosis Medicine 2006 34 (3) :104-106. AC Power Epidemiology of Diabetes ABC type11 diabetes Diabetes 2005 , 1 (1) 7 9Scarlet oral therapy in diabetes sulfonylurea 11, 1984, 16 (10), 3-9. Schade DS, et al A controlled study against placebo in patients in the glimepiride diabetes mellitus diabetes randomized to 19 998, 38 (7), 636-641. Warchman Forouhi-Epidimology diabetes and diabetes-basic facts Medicine 2006 34 (2), the discovery 57-Gd-60Wheeler Aaccident led to the Nobel Prize for Canadian students and researchers , 2005.01 -02. Report of the WHO-Diabetes Health-and-Defiition types of diabetes in 2007, from 1.1 to 4.